Alcohol-related glucose-dependent functional system of error processing

Background Ridderinkhof and colleagues in 2002 [1] reported that moderate “acute” alcohol intake reduces the amplitude of the ‘error-related negativity, a negative deflection in the electroencephalogram associated with error commission in speeded response time tasks. Their work is however, subject to a great deal of criticism. To consider arrow flank tasks responses generally, as cognitive functions as a whole is practically non-informative and to say that blood alcohol concentration of 1.0 per mile is a moderate alcohol dose, when legally it is already intoxication is not correct. Ridderinkhof and colleagues were rather careful in analyzing their results. Their study own our respect since it showed that error commission is related to the functions of the monitoring response system in the mediofrontal brain. The mechanisms for Ridderinkhof’s and colleagues’ work was defined by Holroyd et al [2].